Ocorrência do vírus dengue em crianças de 0 a 10 anos no município de Manaus, Amazonas, 2008

Abstract

During the second half of the twentieth century dengue spread through the tropical and subtropical regions of the planet, threatening the health of 1/3 of world population. Currently, the disease causes about 50 to 100 million cases per year, including more than 500 thousand reported cases of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), severe disease. In Latin America, unlike Asia, the severe form is most prevalent in adults, although recent studies show that it is occurring a shift of gravity to younger age groups, especially in children under 15 years. In this paper we investigate blood samples from children aged 0 to 10 years, in which was established by RT-PCR infectious virus serotypes circulating within the city of Manaus / AM during 2008 in order to Epidemiological aspects of the occurrence of the virus in childhood. Of the 94 children in the study, sixteen (17.0%) were positive for dengue and DENV-3 was the only viral serotype identified. There was no statistically significant association of the result of RT-PCR in relation to sex (p = 0.315). The average time to diagnosis was 2.8 days (SD ± 0.98). All positive samples wreaked havoc in the first quarter of 2008. All areas and eleven districts were positive for DENV-3. In descending order, the neighborhoods that stood out were: Alvorada (18.75%), Compensa and São José Operário (12.50% each). In this study 83.0% of children examined showed negative for dengue by RT-PCR suggesting the occurrence of other febrile illnesses that need to be clarified.