Análise do perfil clínico-dermatológico e imunológico de crianças portadoras do vírus HIV na Fundação de Medicina Tropical do Amazonas

Abstract

The Acquired Immunodeficiency Syndrome (AIDS) constitutes a sub-epidemic in Brazil. Due to the increasing number of women infected by the virus, vertical transmission increasing substantially, and the lack of adequate prophylactic treatment, many children are infected and show manifestations of the disease in early ages. Multiples are the systems affected by the HIV virus, being frequently the skin the first organ to be affected. Skin disorders are the most common manifestation in children with HIV, being sometimes persistent and recurrent. The study objective is to analyze clinic, dermatologic and epidemiological profiles of children carriers of the virus in the City of Manaus aiming to identify the most frequent dermatosis that affect children carriers of HIV virus in the Amazon Region as to try to related these dermatosis with immunologic deterioration in this population. A study took place, where children carriers of HIV virus from the Fundação de Medicina Tropical were studied from March 2007 to July 2008. These children were submitted to dermatological examination viewing to identify dermatosis and also submitted to laboratorial exams such as viral load dosage, CD4+, and CD8+. Specific exams were also realized whenever necessary to give support to dermatosis diagnosis such as direct and culture mycological exam, bacteriologic and histopathological exams. The data collect were stored in data base elaborated using Excel and analyzed using Epi-Info, Windows versions. During the study period, 70 children HIV + were examined, all of them had AIDS and had being contaminated by vertical transmission. The media of children attended was 1.67 and the media of dermatosis by children was 1.73 dermatosis/children and among the 70 youngest, 95.5% had at least one dermatosis during the study period. The most frequent manifestation was atopic dermatitis (22.9%), prurigo estrofulo (20.0%) and wartz (18.6%). There was no statistical difference between the children in the group using HAART and the group that wasn’t using it.