Estudo químico de resíduos madeireiros de Tabebuia serratifolia (Vahl) G. Nicholson, Acacia mangium Willd. e Dipteryx polyphylla Huber

Abstract

The waste of raw materials is one of the main bottlenecks in the wood industry and much of the waste generated in the processing of wood is discarded in inappropriate places, causing damage to the environment. The production of small objects from wood residues is a socio-economic way to add value to these wastes and for this, wood residues of Bignoniaceae and Fabaceae species have been used, which are often not chemically studied because of the difficulties inherent to the wood acquisition. Considering the availability of wood residues through the INCT Project – Madeiras da Amazônia, this study evaluated the wood residue of Tabebuia serratifolia (Bignoniaceae), Acacia mangium and Dipteryx polyphylla (Fabaceae). Fractionation of methanolic extract of T. serratifolia allowed the isolation and identification of naphthoquinones dehydro-α-lapachone, dehydro-iso-α-lapachone and α-lapachone, in addition to lignans paulownin and cycloolivil. The studies on the A. mangium specie allowed the identification of steroids sitosterol, stigmasterol and a spinasterol derivative, 3-methoxy-4-hydroxy-cinnamic acid, methylparaben, 4- hydroxybenzaldehyde and flavonoid 3,4',7,8-tetrahydroxyflavone. With fractionation of the methanolic extract of D. polyphylla it was possible to isolate four isoflavans, with 3', 7-dihydroxy-4'-methoxy-isoflavan and 3',8-dihyd roxy-4',7-dimethoxy-isoflavan unprecedented in literature. Considering the biological potential of the isolated compounds classes, it was performed the antifungal test in the strains of Cryptococcus neoformans (VN1PCN6) and Candida albicans (ATCC 36232) and the naphthoquinone dehydro -iso-α-lapachone distinguished among the tested substances.